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Cell Metab. 2023 Feb 7;35(2):274-286.e10. doi: 10.1016/j.cmet.2022.12.011. Epub 2023 Jan 10.
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Cell Metab. 2023 Feb 7;35(2):287-298.e4. doi: 10.1016/j.cmet.2023.01.001. Epub 2023 Jan 26.
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Am J Clin Nutr. 2023 Jan;117(1):160-174. doi: 10.1016/j.ajcnut.2022.11.008. Epub 2022 Dec 20.
PMID:36789935
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Med Sci Sports Exerc. 2024 Oct 1;56(10):2076-2091. doi: 10.1249/MSS.0000000000003520.