Small vessel disease: mechanisms and clinical implications.
Wardlaw JM, Smith C, Dichgans M.
Lancet Neurol. 2019 Jul;18(7):684-696. doi: 10.1016/S1474-4422(19)30079-1. Epub 2019 May 13.
PMID:31097385
Brain endothelial cell activation and dysfunction associate with and contribute to the development of enlarged perivascular spaces and cerebral small vessel disease.