Transgelin 2 guards T cell lipid metabolism and antitumour function.
Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Marin Falco M, Salvagno C, Emmanuelli A, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, Morales DK, Yu X, Rodriguez PC, Conejo-Garcia JR, Kaczocha M, Vähärautio A, Song M, Cubillos-Ruiz JR.
Nature. 2024 Nov;635(8040):1010-1018. doi: 10.1038/s41586-024-08071-y. Epub 2024 Oct 23.
PMID:39443795
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.
Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E.
Nat Med. 2011 Oct 30;17(11):1498-503. doi: 10.1038/nm.2492.
PMID:22037646
ACSL4 and polyunsaturated lipids support metastatic extravasation and colonization.
Wang Y, Hu M, Cao J, Wang F, Han JR, Wu TW, Li L, Yu J, Fan Y, Xie G, Lian H, Cao Y, Naowarojna N, Wang X, Zou Y.
Cell. 2025 Jan 23;188(2):412-429.e27. doi: 10.1016/j.cell.2024.10.047. Epub 2024 Nov 25.
PMID:39591965
The adipocyte microenvironment and cancer.
Mukherjee A, Bilecz AJ, Lengyel E.
Cancer Metastasis Rev. 2022 Sep;41(3):575-587. doi: 10.1007/s10555-022-10059-x. Epub 2022 Aug 8.
PMID:35941408
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion.
Zou Y, Henry WS, Ricq EL, Graham ET, Phadnis VV, Maretich P, Paradkar S, Boehnke N, Deik AA, Reinhardt F, Eaton JK, Ferguson B, Wang W, Fairman J, Keys HR, Dančík V, Clish CB, Clemons PA, Hammond PT, Boyer LA, Weinberg RA, Schreiber SL.
Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.
Goossens P, Rodriguez-Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, Ulas T, Papantonopoulou O, Van Eck M, Auphan-Anezin N, Bebien M, Verthuy C, Vu Manh TP, Turner M, Dalod M, Schultze JL, Lawrence T.
Cell Metab. 2019 Jun 4;29(6):1376-1389.e4. doi: 10.1016/j.cmet.2019.02.016. Epub 2019 Mar 28.
PMID:30930171
Targeting lipid metabolism in the treatment of ovarian cancer.
Chaudhry S, Thomas SN, Simmons GE Jr.
Oncotarget. 2022 May 25;13:768-783. doi: 10.18632/oncotarget.28241. eCollection 2022.
PMID:35634242
Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils.
Perego M, Tyurin VA, Tyurina YY, Yellets J, Nacarelli T, Lin C, Nefedova Y, Kossenkov A, Liu Q, Sreedhar S, Pass H, Roth J, Vogl T, Feldser D, Zhang R, Kagan VE, Gabrilovich DI.
Sci Transl Med. 2020 Dec 2;12(572):eabb5817. doi: 10.1126/scitranslmed.abb5817.
PMID:33268511
Integrated lipid metabolomics and proteomics analysis reveal the pathogenesis of polycystic ovary syndrome.
Qian Y, Tong Y, Zeng Y, Huang J, Liu K, Xie Y, Chen J, Gao M, Liu L, Zhao J, Hong Y, Nie X.