ACSL4 and polyunsaturated lipids support metastatic extravasation and colonization.
Wang Y, Hu M, Cao J, Wang F, Han JR, Wu TW, Li L, Yu J, Fan Y, Xie G, Lian H, Cao Y, Naowarojna N, Wang X, Zou Y.
Cell. 2025 Jan 23;188(2):412-429.e27. doi: 10.1016/j.cell.2024.10.047. Epub 2024 Nov 25.
Transgelin 2 guards T cell lipid metabolism and antitumour function.
Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Marin Falco M, Salvagno C, Emmanuelli A, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, Morales DK, Yu X, Rodriguez PC, Conejo-Garcia JR, Kaczocha M, Vähärautio A, Song M, Cubillos-Ruiz JR.
Nature. 2024 Nov;635(8040):1010-1018. doi: 10.1038/s41586-024-08071-y. Epub 2024 Oct 23.
The adipocyte microenvironment and cancer.
Mukherjee A, Bilecz AJ, Lengyel E.
Cancer Metastasis Rev. 2022 Sep;41(3):575-587. doi: 10.1007/s10555-022-10059-x. Epub 2022 Aug 8.
Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.
Weiss JM, Davies LC, Karwan M, Ileva L, Ozaki MK, Cheng RY, Ridnour LA, Annunziata CM, Wink DA, McVicar DW.
J Clin Invest. 2018 Aug 31;128(9):3794-3805. doi: 10.1172/JCI99169. Epub 2018 Jul 30.
Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.
Goossens P, Rodriguez-Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, Ulas T, Papantonopoulou O, Van Eck M, Auphan-Anezin N, Bebien M, Verthuy C, Vu Manh TP, Turner M, Dalod M, Schultze JL, Lawrence T.
Cell Metab. 2019 Jun 4;29(6):1376-1389.e4. doi: 10.1016/j.cmet.2019.02.016. Epub 2019 Mar 28.
Integrated lipid metabolomics and proteomics analysis reveal the pathogenesis of polycystic ovary syndrome.
Qian Y, Tong Y, Zeng Y, Huang J, Liu K, Xie Y, Chen J, Gao M, Liu L, Zhao J, Hong Y, Nie X.
J Transl Med. 2024 Apr 17;22(1):364. doi: 10.1186/s12967-024-05167-x.
CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis.
Lamperis SM, McMahon KM, Calvert AE, Rink JS, Vasan K, Pandkar MR, Crentsil EU, Chalmers ZR, McDonald NR, Kosmala CJ, Bonini MG, Matei D, Gordon LI, Chandel NS, Thaxton CS.
Proc Natl Acad Sci U S A. 2025 Jun 3;122(22):e2502876122. doi: 10.1073/pnas.2502876122. Epub 2025 May 30.
Butyrate as a Potential Modulator in Gynecological Disease Progression.
Kim N, Yang C.
Nutrients. 2024 Dec 4;16(23):4196. doi: 10.3390/nu16234196.
Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin.
Koizume S, Kanayama T, Kimura Y, Hirano H, Takahashi T, Ota Y, Miyazaki K, Yoshihara M, Nakamura Y, Yokose T, Kato H, Takenaka K, Sato S, Tadokoro H, Miyagi E, Miyagi Y.
Cancer Sci. 2023 Jun;114(6):2485-2498. doi: 10.1111/cas.15774. Epub 2023 Mar 21.
Effects of Androgen Excess-Related Metabolic Disturbances on Granulosa Cell Function and Follicular Development.
Liao B, Qi X, Yun C, Qiao J, Pang Y.
Front Endocrinol (Lausanne). 2022 Feb 14;13:815968. doi: 10.3389/fendo.2022.815968. eCollection 2022.
