Sigh Breaths for Trauma Patients Receiving Mechanical Ventilation: Take a Deep Breath.
Bellani G, Pesenti A.
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Sigh Ventilation in Patients With Trauma: The SiVent Randomized Clinical Trial.
Albert RK, Jurkovich GJ, Connett J, Helgeson ES, Keniston A, Voelker H, Lindberg S, Proper JL, Bochicchio G, Stein DM, Cain C, Tesoriero R, Brown CVR, Davis J, Napolitano L, Carver T, Cipolle M, Cardenas L, Minei J, Nirula R, Doucet J, Miller PR, Johnson J, Inaba K, Kao L.
JAMA. 2023 Nov 28;330(20):1982-1990. doi: 10.1001/jama.2023.21739.
Noninvasive Ventilation.
Ramanathan R, Biniwale M.
Crit Care Nurs Clin North Am. 2024 Mar;36(1):51-67. doi: 10.1016/j.cnc.2023.11.001. Epub 2023 Nov 29.
Intermittent sigh breaths during high-frequency oscillatory ventilation among newborn infants.
Jeon GW.
Clin Exp Pediatr. 2025 Jul;68(7):486-488. doi: 10.3345/cep.2025.00549. Epub 2025 Apr 16.
Effect of perioperative sigh ventilation on postoperative hypoxemia and pulmonary complications after on-pump cardiac surgery (E-SIGHT): study protocol for a randomized controlled trial.
Wang Z, Cheng Q, Huang S, Sun J, Xu J, Xie J, Cao H, Guo F.
Trials. 2024 Sep 4;25(1):585. doi: 10.1186/s13063-024-08416-y.
Sigh Breaths in Patients With Trauma Receiving Mechanical Ventilation.
Albert RK, Helgeson ES.
JAMA. 2024 Mar 12;331(10):887-888. doi: 10.1001/jama.2024.0117.
Pressure support ventilation, sigh adjunct to pressure support ventilation, and neurally adjusted ventilatory assist in infants after cardiac surgery: A physiologic crossover randomized study.
Bonacina D, Bronco A, Nacoti M, Ferrari F, Fazzi F, Bonanomi E, Bellani G.
Pediatr Pulmonol. 2019 Jul;54(7):1078-1086. doi: 10.1002/ppul.24335. Epub 2019 Apr 19.
Sigh maneuver protects healthy lungs during mechanical ventilation in adult Wistar rats.
da Silva ACL, de Matos NA, de Souza ABF, Castro TF, Cândido LDS, Oliveira MADGS, Costa GP, Talvani A, Cangussú SD, Bezerra FS.
Exp Biol Med (Maywood). 2020 Sep;245(15):1404-1413. doi: 10.1177/1535370220940995. Epub 2020 Jul 8.
Pressure support ventilation + sigh in acute hypoxemic respiratory failure patients: study protocol for a pilot randomized controlled trial, the PROTECTION trial.
Mauri T, Foti G, Fornari C, Constantin JM, Guerin C, Pelosi P, Ranieri M, Conti S, Tubiolo D, Rondelli E, Lovisari F, Fossali T, Spadaro S, Grieco DL, Navalesi P, Calamai I, Becher T, Roca O, Wang YM, Knafelj R, Cortegiani A, Mancebo J, Brochard L, Pesenti A; Protection Study Group.
Trials. 2018 Aug 29;19(1):460. doi: 10.1186/s13063-018-2828-8.
Effects of Sigh on Regional Lung Strain and Ventilation Heterogeneity in Acute Respiratory Failure Patients Undergoing Assisted Mechanical Ventilation.
Mauri T, Eronia N, Abbruzzese C, Marcolin R, Coppadoro A, Spadaro S, Patroniti N, Bellani G, Pesenti A.
Crit Care Med. 2015 Sep;43(9):1823-31. doi: 10.1097/CCM.0000000000001083.
