HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation.
Gao Y, Liu Y, Zheng D, Ho C, Wen D, Sun J, Huang L, Liu Y, Li Q, Zhang Y.
Int J Biol Sci. 2022 Sep 11;18(15):5724-5739. doi: 10.7150/ijbs.76140. eCollection 2022.
Using network pharmacology to discover potential drugs for hypertrophic scars.
Zhang Y, Li X, Yu Q, Lv X, Li C, Wang L, Liu Y, Wang Q, Yang Z, Fu X, Xiao R.
Br J Dermatol. 2024 Sep 18;191(4):592-604. doi: 10.1093/bjd/ljae234.
Histone lactylation regulates autophagy of hyperplastic scar fibroblasts by inhibiting the transcriptional activity of phosphatase and tensin homologue.
Liu X, Wang B.
Wound Repair Regen. 2024 Sep-Oct;32(5):725-734. doi: 10.1111/wrr.13188. Epub 2024 May 19.
Bacterial colonization contributes to pathological scar formation via the regulation of inflammatory response.
Yang N, Zhang H, Zhang Y, Lin B, Huang R, Cui T, Li X.
J Transl Med. 2025 May 21;23(1):569. doi: 10.1186/s12967-025-06585-1.
ZnO colludes with C. acnes in healing delay and Scar hyperplasia by barrier destruction.
Zhang F, Wang T, Wang W, Lv Y, Qu Y, Liu D, Sun X, Kong X, Wang C, Shi J.
J Nanobiotechnology. 2025 May 31;23(1):404. doi: 10.1186/s12951-025-03414-x.
Radial Sclerosing Lesion (Radial Scar): Radiologic-Pathologic Correlation.
Yan P, Bean G, Bao J, Dashevsky BZ.
J Breast Imaging. 2024 Nov 5;6(6):646-657. doi: 10.1093/jbi/wbae046.
Clinical Efficacy and Safety of Pulsed Dye Laser Combined with Pingyangmycin on Hyperplastic Scar after Acne.
Guo R, Xuan W, He X, Xu K.
Mediators Inflamm. 2022 Aug 28;2022:3305107. doi: 10.1155/2022/3305107. eCollection 2022.
[Differential expression profile of microRNA between hyperplastic scar and normal skin].
Ning P, Liu DW, Mao YG, Peng Y, Lin ZW, Liu DM.
Zhonghua Yi Xue Za Zhi. 2012 Mar 13;92(10):692-4.
Mechanism of IFITM1 regulating epidural scar hyperplasia after laminectomy through SMAD3/CBR4 pathway.
Wang H, Zhu Z, Liu J.
Front Immunol. 2025 Sep 3;16:1628970. doi: 10.3389/fimmu.2025.1628970. eCollection 2025.
Multifunctional hydrogel dressing composed of trichosanthes polysaccharide and carboxymethyl chitosan accelerates cachectic wound healing and reduces scar hyperplasia.
Chen G, Yang C, Xu X, Yang L, Zhang Y, Cai C, Muhitdinov B, Turaev A, Qiu H, Huang S, Xu Q, Wang H, Huang Y.
Carbohydr Polym. 2025 Jun 1;357:123378. doi: 10.1016/j.carbpol.2025.123378. Epub 2025 Feb 17.
