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Glucocorticoid activation by HSD11B1 limits T cell-driven interferon signaling and response to PD-1 blockade in melanoma.
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J Immunother Cancer. 2023 Apr 7;11(4):e004150. doi: 10.1136/jitc-2021-004150.
Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner.
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Abrogation of RAB27A expression transiently affects melanoma cell proliferation.
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Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion.
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Melanoma tumors frequently acquire LRP2/megalin expression, which modulates melanoma cell proliferation and survival rates.
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Cell division cycle-associated protein 1 as a new melanoma-associated antigen.
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Recombinant human stem cell factor does exert minor stimulation of growth in small cell lung cancer and melanoma cell lines.
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IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma.
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