Is REM Density a Measure of Arousal during Sleep?
Barbato G.
Brain Sci. 2023 Feb 21;13(3):378. doi: 10.3390/brainsci13030378.
Methods for REM Sleep Density Analysis: A Scoping Review.
Kishi TT, Andersen ML, Luciano YM, Kakazu VA, Tufik S, Pires GN.
Clocks Sleep. 2023 Dec 14;5(4):793-805. doi: 10.3390/clockssleep5040051.
Prefrontal cortical regulation of REM sleep.
Hong J, Lozano DE, Beier KT, Chung S, Weber F.
Nat Neurosci. 2023 Oct;26(10):1820-1832. doi: 10.1038/s41593-023-01398-1. Epub 2023 Sep 21.
REM density in Parkinson's disease: association with motor, cognitive, autonomic function, and dopaminergic medication.
Dagay A, Katzav S, Elisha N, Volkov J, Tauman R, Giladi N, Hausdorff JM, Mirelman A, Zitser J.
NPJ Parkinsons Dis. 2025 Jul 14;11(1):211. doi: 10.1038/s41531-025-01057-1.
REM density predicts rapid antidepressant response to ketamine in individuals with treatment-resistant depression.
Kheirkhah M, Duncan WC Jr, Yuan Q, Wang PR, Jamalabadi H, Leistritz L, Walter M, Goldman D, Zarate CA Jr, Hejazi NS.
Neuropsychopharmacology. 2025 May;50(6):941-946. doi: 10.1038/s41386-025-02066-7. Epub 2025 Feb 15.
Time to reconsider REM density in sleep research.
Saleh C, Diederich NJ, Schroeder LA, Schmidt M, Rüegg S, Khatami R.
Clin Neurophysiol. 2022 May;137:63-65. doi: 10.1016/j.clinph.2022.02.011. Epub 2022 Feb 25.
Depression and Sleep.
Steiger A, Pawlowski M.
Int J Mol Sci. 2019 Jan 31;20(3):607. doi: 10.3390/ijms20030607.
REM density is associated with treatment response in major depression: Antidepressant pharmacotherapy vs. psychotherapy.
Lechinger J, Koch J, Weinhold SL, Seeck-Hirschner M, Stingele K, Kropp-Näf C, Braun M, Drews HJ, Aldenhoff J, Huchzermeier C, Göder R.
J Psychiatr Res. 2021 Jan;133:67-72. doi: 10.1016/j.jpsychires.2020.12.009. Epub 2020 Dec 9.
Scoring of REM density.
Tachibana N, Sugita Y, Terashima K, Teshima Y, Shimizu T, Hishikawa Y.
Neurology. 1994 May;44(5):987-8. doi: 10.1212/wnl.44.5.987-c.
REM Density, Leg Movements, and REM Sleep without Atonia: Differentiating Type 1 from Type 2 Narcolepsy Through Polysomnographic Analysis, a Preliminary Study.
Xu J, Zhao W, Yan Z, Lu S, Zhang Y, Zang K, Tang J, Huang W.
Nat Sci Sleep. 2025 Sep 2;17:2079-2089. doi: 10.2147/NSS.S535919. eCollection 2025.
