Relative biological effectiveness (RBE) values for proton beam therapy. Variations as a function of biological endpoint, dose, and linear energy transfer.
Paganetti H.
Phys Med Biol. 2014 Nov 21;59(22):R419-72. doi: 10.1088/0031-9155/59/22/R419. Epub 2014 Oct 31.
Does the uncertainty in relative biological effectiveness affect patient treatment in proton therapy?
Sørensen BS, Pawelke J, Bauer J, Burnet NG, Dasu A, Høyer M, Karger CP, Krause M, Schwarz M, Underwood TSA, Wagenaar D, Whitfield GA, Lühr A.
Radiother Oncol. 2021 Oct;163:177-184. doi: 10.1016/j.radonc.2021.08.016. Epub 2021 Sep 1.
Modelling variable proton relative biological effectiveness for treatment planning.
McNamara A L, Willers H, Paganetti H.
Br J Radiol. 2020 Mar;93(1107):20190334. doi: 10.1259/bjr.20190334. Epub 2019 Nov 18.
Hypoxia adapted relative biological effectiveness models for proton therapy: a simulation study.
Garrido-Hernandez G, Henjum H, Høiskar MK, Dahle TJ, Redalen KR, Ytre-Hauge KS.
Biomed Phys Eng Express. 2022 Nov 4;8(6). doi: 10.1088/2057-1976/ac9b5d.
Relative Biological Effectiveness (RBE) of [(64)Cu]Cu and [(177)Lu]Lu-NOTA-panitumumab F (ab')(2) radioimmunotherapeutic agents vs. gamma-radiation for decreasing the clonogenic survival in vitro of human pancreatic ductal adenocarcinoma (PDAC) cells.
Boyle AJ, Cai Z, O'Brien S, Crick J, Angers S, Reilly RM.
Nucl Med Biol. 2023 Jul-Aug;122-123:108367. doi: 10.1016/j.nucmedbio.2023.108367. Epub 2023 Jul 17.
Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study.
Yang Y, Muller OM, Shiraishi S, Harper M, Amundson AC, Wong WW, McGee LA, Rwigema JM, Schild SE, Bues M, Fatyga M, Anderson JD, Patel SH, Foote RL, Liu W.
Front Oncol. 2022 Mar 3;12:843175. doi: 10.3389/fonc.2022.843175. eCollection 2022.
The physical separation between the LET associated with the ultimate relative biological effect (RBE) and the maximum LET in a proton or ion beam.
Jones B, Hill MA.
Biomed Phys Eng Express. 2020 Jul 7;6(5):055001. doi: 10.1088/2057-1976/ab9e13.
Relative Biological Effectiveness of High LET Particles on the Reproductive System and Fetal Development.
Wang B, Yasuda H.
Life (Basel). 2020 Nov 20;10(11):298. doi: 10.3390/life10110298.
Relative Biological Effectiveness Uncertainties and Implications for Beam Arrangements and Dose Constraints in Proton Therapy.
Paganetti H, Giantsoudi D.
Semin Radiat Oncol. 2018 Jun;28(3):256-263. doi: 10.1016/j.semradonc.2018.02.010.
A comparison of mechanism-inspired models for particle relative biological effectiveness (RBE).
Stewart RD, Carlson DJ, Butkus MP, Hawkins R, Friedrich T, Scholz M.
Med Phys. 2018 Nov;45(11):e925-e952. doi: 10.1002/mp.13207.
