Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity.
Scott-Solomon E, Brielle S, Mann AO, Khoury MJ, Peng J, Tellez L, Harrigan M, Ziogas M, Pasolli HA, Cassandras M, Getzler AJ, Freeman R, Zhang B, Shwartz Y, Agudo J, Franklin RA, Hsu YC.
Cell. 2026 Jan 8;189(1):252-271.e19. doi: 10.1016/j.cell.2025.10.042. Epub 2025 Nov 26.
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Autoimmunity: alopecia areata.
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J Investig Dermatol Symp Proc. 2004 Jan;9(1):73-8. doi: 10.1111/j.1087-0024.2004.00835.x.
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Relationship between follicular nerve supply and alopecia.