Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management.
Tang G, Li S, Zhang C, Chen H, Wang N, Feng Y.
Acta Pharm Sin B. 2021 Sep;11(9):2749-2767. doi: 10.1016/j.apsb.2020.12.020. Epub 2021 Feb 2.
Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy.
Liu S, Zhao Y, Lu S, Zhang T, Lindenmeyer MT, Nair V, Gies SE, Wu G, Nelson RG, Czogalla J, Aypek H, Zielinski S, Liao Z, Schaper M, Fermin D, Cohen CD, Delic D, Krebs CF, Grahammer F, Wiech T, Kretzler M, Meyer-Schwesinger C, Bonn S, Huber TB.
Genome Med. 2023 Jan 10;15(1):2. doi: 10.1186/s13073-022-01145-4.
Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging.
Wang Z, Fu W, Huo M, He B, Liu Y, Tian L, Li W, Zhou Z, Wang B, Xia J, Chen Y, Wei J, Abliz Z.
Acta Pharm Sin B. 2021 Nov;11(11):3665-3677. doi: 10.1016/j.apsb.2021.05.013. Epub 2021 May 20.
The New Biology of Diabetic Kidney Disease-Mechanisms and Therapeutic Implications.
Lytvyn Y, Bjornstad P, van Raalte DH, Heerspink HL, Cherney DZI.
Endocr Rev. 2020 Apr 1;41(2):202-31. doi: 10.1210/endrev/bnz010.
The beneficial effects of astragaloside IV on ameliorating diabetic kidney disease.
Gao Y, Su X, Xue T, Zhang N.
Biomed Pharmacother. 2023 Jul;163:114598. doi: 10.1016/j.biopha.2023.114598. Epub 2023 May 5.
Recent therapeutic targets in diabetic nephropathy.
Mohsen M, Elberry AA, Mohamed Rabea A, Abdelrahim MEA, Hussein RRS.
Int J Clin Pract. 2021 Nov;75(11):e14650. doi: 10.1111/ijcp.14650. Epub 2021 Aug 10.
Pharmacological treatment of hyperglycemia in type 2 diabetes.
Taylor SI, Yazdi ZS, Beitelshees AL.
J Clin Invest. 2021 Jan 19;131(2):e142243. doi: 10.1172/JCI142243.
Astragaloside IV ameliorates diabetic nephropathy in db/db mice by inhibiting NLRP3 inflammasome-mediated inflammation.
Feng H, Zhu X, Tang Y, Fu S, Kong B, Liu X.
Int J Mol Med. 2021 Aug;48(2):164. doi: 10.3892/ijmm.2021.4996. Epub 2021 Jul 19.
Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.
Salem RM, Todd JN, Sandholm N, Cole JB, Chen WM, Andrews D, Pezzolesi MG, McKeigue PM, Hiraki LT, Qiu C, Nair V, Di Liao C, Cao JJ, Valo E, Onengut-Gumuscu S, Smiles AM, McGurnaghan SJ, Haukka JK, Harjutsalo V, Brennan EP, van Zuydam N, Ahlqvist E, Doyle R, Ahluwalia TS, Lajer M, Hughes MF, Park J, Skupien J, Spiliopoulou A, Liu A, Menon R, Boustany-Kari CM, Kang HM, Nelson RG, Klein R, Klein BE, Lee KE, Gao X, Mauer M, Maestroni S, Caramori ML, de Boer IH, Miller RG, Guo J, Boright AP, Tregouet D, Gyorgy B, Snell-Bergeon JK, Maahs DM, Bull SB, Canty AJ, Palmer CNA, Stechemesser L, Paulweber B, Weitgasser R, Sokolovska J, Rovīte V, Pīrāgs V, Prakapiene E, Radzeviciene L, Verkauskiene R, Panduru NM, Groop LC, McCarthy MI, Gu HF, Möllsten A, Falhammar H, Brismar K, Martin F, Rossing P, Costacou T, Zerbini G, Marre M, Hadjadj S, McKnight AJ, Forsblom C, McKay G, Godson C, Maxwell AP, Kretzler M, Susztak K, Colhoun HM, Krolewski A, Paterson AD, Groop PH, Rich SS, Hirschhorn JN, Florez JC; SUMMIT Consortium, DCCT/EDIC Research Group, GENIE Consortium.
J Am Soc Nephrol. 2019 Oct;30(10):2000-2016. doi: 10.1681/ASN.2019030218. Epub 2019 Sep 19.
Astragaloside IV acts through multi-scale mechanisms to effectively reduce diabetic nephropathy.
Wang E, Wang L, Ding R, Zhai M, Ge R, Zhou P, Wang T, Fang H, Wang J, Huang J.
Pharmacol Res. 2020 Jul;157:104831. doi: 10.1016/j.phrs.2020.104831. Epub 2020 Apr 24.
