GABP Promotes Mesangial Cell Proliferation and Renal Fibrosis Through GLI1 in Diabetic Nephropathy.
Du L, Liu S, Lu Y, Ren D, Yu X, Hu Y, Yang T, Yang Q, Ming J, Zhang J, Yin X, Lu Q.
Adv Sci (Weinh). 2025 Apr;12(15):e2407462. doi: 10.1002/advs.202407462. Epub 2025 Feb 22.
Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway.
Zhao L, Lan Z, Peng L, Wan L, Liu D, Tan X, Tang C, Chen G, Liu H.
Cell Prolif. 2022 Sep;55(9):e13278. doi: 10.1111/cpr.13278. Epub 2022 Jun 22.
SBP1 contributes to mesangial proliferation and inflammation through mitochondrial respiration in glomerulus during IgA nephropathy.
Kim J, Lee JH, Jang SH, Lee EY, Lee M, Park S, Moon JS.
Free Radic Biol Med. 2024 Nov 20;225:711-725. doi: 10.1016/j.freeradbiomed.2024.10.313. Epub 2024 Oct 31.
Glycine decarboxylase advances IgA nephropathy by boosting mesangial cell proliferation through the pyrimidine pathway.
Xiong Y, Zeng F, Luo K, Wang L, Li M, Chen Y, Huang T, Xu C, Xu G, Zou H.
EMBO Mol Med. 2025 Nov;17(11):3039-3063. doi: 10.1038/s44321-025-00315-2. Epub 2025 Oct 13.
SUMO1 Promotes Mesangial Cell Proliferation Through Inhibiting Autophagy in a Cell Model of IgA Nephropathy.
Tan X, Liu Y, Liu D, Tang X, Xia M, Chen G, He L, Zhu X, Liu H.
Front Med (Lausanne). 2022 Mar 31;9:834164. doi: 10.3389/fmed.2022.834164. eCollection 2022.
Soluble CD89 is a critical factor for mesangial proliferation in childhood IgA nephropathy.
Cambier A, Gleeson PJ, Abbad L, Canesi F, da Silva J, Bex-Coudrat J, Deschênes G, Boyer O, Rabant M, Ulinski T, Hogan J, Peuchmaur M, Berthelot L, Monteiro RC.
Kidney Int. 2022 Feb;101(2):274-287. doi: 10.1016/j.kint.2021.09.023. Epub 2021 Oct 28.
Prrx1 promotes mesangial cell proliferation and kidney fibrosis through YAP in diabetic nephropathy.
Xu L, Shi J, Li H, Liu Y, Wang J, Li X, Ren D, Liu S, Wang H, Lu Y, Song J, Du L, Lu Q, Yin X.
J Pharm Anal. 2025 Oct;15(10):101247. doi: 10.1016/j.jpha.2025.101247. Epub 2025 Feb 28.
Tenascin-C promotes the proliferation and fibrosis of mesangial cells in diabetic nephropathy through the beta-catenin pathway.
Pang X, Hou X, Hu C, Lu S, Gan H, Yang H, Xiang S, Zhou J, Gao H, Chen S.
Int Urol Nephrol. 2023 Oct;55(10):2507-2516. doi: 10.1007/s11255-023-03547-8. Epub 2023 Mar 24.
Tetrandrine inhibits the proliferation of mesangial cells induced by enzymatically deglycosylated human IgA1 via IgA receptor/MAPK/NF-kappaB signaling pathway.
Xu W, Song W, Chen S, Jin S, Xue X, Min J, Wang X, You P.
Front Pharmacol. 2023 Jun 15;14:1150829. doi: 10.3389/fphar.2023.1150829. eCollection 2023.
YY1/HIF-1alpha/mROS positive-feedback loop exacerbates glomerular mesangial cell proliferation in mouse early diabetic kidney disease.
Yang TT, Shao YT, Cheng Q, He YT, Qiu Z, Pan DD, Zhang HM, Jiang ZZ, Yan M, Ying CJ, Li BJ, Liu JJ, Qian ST, Wang T, Yin XX, Lu Q.
Acta Pharmacol Sin. 2025 Jul;46(7):1974-1989. doi: 10.1038/s41401-025-01498-7. Epub 2025 Mar 4.
