Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial.
Han JK, Bachert C, Fokkens W, Desrosiers M, Wagenmann M, Lee SE, Smith SG, Martin N, Mayer B, Yancey SW, Sousa AR, Chan R, Hopkins C; SYNAPSE study investigators.
Lancet Respir Med. 2021 Oct;9(10):1141-1153. doi: 10.1016/S2213-2600(21)00097-7. Epub 2021 Apr 16.
Mepolizumab for chronic rhinosinusitis with nasal polyps: Treatment efficacy by comorbidity and blood eosinophil count.
Bachert C, Sousa AR, Han JK, Schlosser RJ, Sowerby LJ, Hopkins C, Maspero JF, Smith SG, Kante O, Karidi-Andrioti DE, Mayer B, Chan RH, Yancey SW, Chaker AM.
J Allergy Clin Immunol. 2022 May;149(5):1711-1721.e6. doi: 10.1016/j.jaci.2021.10.040. Epub 2022 Jan 7.
EUFOREA expert board meeting on uncontrolled severe chronic rhinosinusitis with nasal polyps (CRSwNP) and biologics: Definitions and management.
Bachert C, Han JK, Wagenmann M, Hosemann W, Lee SE, Backer V, Mullol J, Gevaert P, Klimek L, Prokopakis E, Knill A, Cavaliere C, Hopkins C, Hellings P.
J Allergy Clin Immunol. 2021 Jan;147(1):29-36. doi: 10.1016/j.jaci.2020.11.013. Epub 2020 Nov 20.
[Rhinosinusitis].
Hassid S.
Rev Med Brux. 2013 Sep;34(4):257-61.
Endotypes of chronic rhinosinusitis based on inflammatory and remodeling factors.
Wang X, Sima Y, Zhao Y, Zhang N, Zheng M, Du K, Wang M, Wang Y, Hao Y, Li Y, Liu M, Piao Y, Liu C, Tomassen P, Zhang L, Bachert C.
J Allergy Clin Immunol. 2023 Feb;151(2):458-468. doi: 10.1016/j.jaci.2022.10.010. Epub 2022 Oct 19.
Perioperative adjuvant therapy with short course of dupilumab with ESS for recurrent CRSwNP.
Pelletier A, Endam LM, Gonzalez E, Jannat S, Irani T, Desrosiers M.
Int Forum Allergy Rhinol. 2025 Mar;15(3):227-238. doi: 10.1002/alr.23471. Epub 2024 Oct 23.
An unusual nasal polyp.
Morvan JB, Maso V, Benchetrit M, Dagain A, Desse N.
Eur Ann Otorhinolaryngol Head Neck Dis. 2021 Dec;138(6):493-496. doi: 10.1016/j.anorl.2021.06.005. Epub 2021 Jun 25.
Mediators in nasal polyposis.
Bachert C, Gevaert P, Holtappels G, van Cauwenberge P.
Curr Allergy Asthma Rep. 2002 Nov;2(6):481-7. doi: 10.1007/s11882-002-0088-9.
Laryngopharyngeal Reflux and Olfaction Disorders. Is There Any Connection? A Scoping Review.
Florou V, Karkos PD, Marini K, Lechien JR, Paikos D, Skoulakis C, Hajiioannou J.
Maedica (Bucur). 2022 Jun;17(2):471-480. doi: 10.26574/maedica.2022.17.2.471.
Dupilumab prevents nasal epithelial function alteration by IL-4 in vitro: Evidence for its efficacy.
Fieux M, Carsuzaa F, Bellanger Y, Bartier S, Fournier V, Lecron JC, Bainaud M, Louis B, Tringali S, Dufour X, Coste A, Favot L, Bequignon E.
Int Forum Allergy Rhinol. 2024 Aug;14(8):1337-1349. doi: 10.1002/alr.23343. Epub 2024 Mar 11.
