The TLR7/9 adaptors TASL and TASL2 mediate IRF5-dependent antiviral responses and autoimmunity in mouse.
Drobek A, Bernaleau L, Delacrétaz M, Calderon Copete S, Royer-Chardon C, Longepierre M, Monguió-Tortajada M, Korzeniowski J, Rotman S, Marquis J, Rebsamen M.
Nat Commun. 2025 Jan 24;16(1):967. doi: 10.1038/s41467-024-55692-y.
PMID:39856058
Reconstitution of SPO11-dependent double-strand break formation.
Zheng Z, Zheng L, Arter M, Liu K, Yamada S, Ontoso D, Kim S, Keeney S.
bioRxiv [Preprint]. 2024 Nov 21:2024.11.20.624382. doi: 10.1101/2024.11.20.624382.
PMID:39605552
The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes.
Rimann I, Gonzalez-Quintial R, Baccala R, Kiosses WB, Teijaro JR, Parker CG, Li X, Beutler B, Kono DH, Theofilopoulos AN.
Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2200544119. doi: 10.1073/pnas.2200544119. Epub 2022 Mar 29.