High level positive end expiratory pressure (PEEP) in acute respiratory insufficiency.
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Releasing high positive end-expiratory pressure to a low level generates a pronounced increase in particle flow from the airways.
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High level positive end expiratory pressure in a trauma patient with adult respiratory distress syndrome.
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High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial.
PROVE Network Investigators for the Clinical Trial Network of the European Society of Anaesthesiology; Hemmes SN, Gama de Abreu M, Pelosi P, Schultz MJ.
Lancet. 2014 Aug 9;384(9942):495-503. doi: 10.1016/S0140-6736(14)60416-5. Epub 2014 Jun 2.
PMID:24894577
The increase in cardiac output induced by a decrease in positive end-expiratory pressure reliably detects volume responsiveness: the PEEP-test study.
Lai C, Shi R, Beurton A, Moretto F, Ayed S, Fage N, Gavelli F, Pavot A, Dres M, Teboul JL, Monnet X.
Preoxygenation and prevention of desaturation during emergency airway management.
Weingart SD, Levitan RM.
Ann Emerg Med. 2012 Mar;59(3):165-75.e1. doi: 10.1016/j.annemergmed.2011.10.002. Epub 2011 Nov 3.
PMID:22050948
High versus low positive end-expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute lung injury and acute respiratory distress syndrome.
Santa Cruz R, Villarejo F, Irrazabal C, Ciapponi A.
Cochrane Database Syst Rev. 2021 Mar 30;3(3):CD009098. doi: 10.1002/14651858.CD009098.pub3.
PMID:33784416
High positive end-expiratory pressure ventilation mitigates the progression from unilateral pulmonary contusion to ARDS: An animal study.
Landeck T, Schwarz H, Hammermüller S, Noreikat K, Reske S, Gottschaldt U, Nestler C, Wolf SJ, Ramm J, Lange M, Wrigge H, Girrbach F, Brehm W, Reske AW.
J Trauma Acute Care Surg. 2024 Feb 1;96(2):287-296. doi: 10.1097/TA.0000000000004077. Epub 2023 Jun 19.
PMID:37335128
Ventilation-induced acute kidney injury in acute respiratory failure: Do PEEP levels matter?
Benites MH, Suarez-Sipmann F, Kattan E, Cruces P, Retamal J.
Crit Care. 2025 Mar 21;29(1):130. doi: 10.1186/s13054-025-05343-5.
PMID:40114273
High Positive End-Expiratory Pressure Renders Spontaneous Effort Noninjurious.
Morais CCA, Koyama Y, Yoshida T, Plens GM, Gomes S, Lima CAS, Ramos OPS, Pereira SM, Kawaguchi N, Yamamoto H, Uchiyama A, Borges JB, Vidal Melo MF, Tucci MR, Amato MBP, Kavanagh BP, Costa ELV, Fujino Y.
Am J Respir Crit Care Med. 2018 May 15;197(10):1285-1296. doi: 10.1164/rccm.201706-1244OC.
PMID:29323536
High positive end expiratory pressure levels affect hemodynamics in elderly patients with hypertension admitted to the intensive care unit: a prospective cohort study.
Zhou L, Cai G, Xu Z, Weng Q, Ye Q, Chen C.
BMC Pulm Med. 2019 Nov 27;19(1):224. doi: 10.1186/s12890-019-0965-9.