High level positive end expiratory pressure (PEEP) in acute respiratory insufficiency.
Releasing high positive end-expiratory pressure to a low level generates a pronounced increase in particle flow from the airways.
High level positive end expiratory pressure in a trauma patient with adult respiratory distress syndrome.
High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial.
PROVE Network Investigators for the Clinical Trial Network of the European Society of Anaesthesiology; Hemmes SN, Gama de Abreu M, Pelosi P, Schultz MJ.
Lancet. 2014 Aug 9;384(9942):495-503. doi: 10.1016/S0140-6736(14)60416-5. Epub 2014 Jun 2.
High versus low positive end-expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute lung injury and acute respiratory distress syndrome.
Santa Cruz R, Villarejo F, Irrazabal C, Ciapponi A.
Cochrane Database Syst Rev. 2021 Mar 30;3(3):CD009098. doi: 10.1002/14651858.CD009098.pub3.
Ventilatory targets following brain injury.
Taran S, Wahlster S, Robba C.
Curr Opin Crit Care. 2023 Apr 1;29(2):41-49. doi: 10.1097/MCC.0000000000001018. Epub 2023 Jan 20.
The increase in cardiac output induced by a decrease in positive end-expiratory pressure reliably detects volume responsiveness: the PEEP-test study.
Lai C, Shi R, Beurton A, Moretto F, Ayed S, Fage N, Gavelli F, Pavot A, Dres M, Teboul JL, Monnet X.
Crit Care. 2023 Apr 9;27(1):136. doi: 10.1186/s13054-023-04424-7.
Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data.
Neto AS, Hemmes SN, Barbas CS, Beiderlinden M, Fernandez-Bustamante A, Futier E, Gajic O, El-Tahan MR, Ghamdi AA, Günay E, Jaber S, Kokulu S, Kozian A, Licker M, Lin WQ, Maslow AD, Memtsoudis SG, Reis Miranda D, Moine P, Ng T, Paparella D, Ranieri VM, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Amato MB, Costa EL, de Abreu MG, Pelosi P, Schultz MJ; PROVE Network Investigators.
Lancet Respir Med. 2016 Apr;4(4):272-80. doi: 10.1016/S2213-2600(16)00057-6. Epub 2016 Mar 4.
Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece.
Thille AW, Gacouin A, Coudroy R, Ehrmann S, Quenot JP, Nay MA, Guitton C, Contou D, Labro G, Reignier J, Pradel G, Beduneau G, Dangers L, Saccheri C, Prat G, Lacave G, Sedillot N, Terzi N, La Combe B, Mira JP, Romen A, Azais MA, Rouzé A, Devaquet J, Delbove A, Dres M, Bourenne J, Lautrette A, de Keizer J, Ragot S, Frat JP; REVA Research Network.
N Engl J Med. 2022 Nov 17;387(20):1843-1854. doi: 10.1056/NEJMoa2209041. Epub 2022 Oct 26.
High positive end expiratory pressure levels affect hemodynamics in elderly patients with hypertension admitted to the intensive care unit: a prospective cohort study.
Zhou L, Cai G, Xu Z, Weng Q, Ye Q, Chen C.
BMC Pulm Med. 2019 Nov 27;19(1):224. doi: 10.1186/s12890-019-0965-9.
High Positive End-Expiratory Pressure Renders Spontaneous Effort Noninjurious.
Morais CCA, Koyama Y, Yoshida T, Plens GM, Gomes S, Lima CAS, Ramos OPS, Pereira SM, Kawaguchi N, Yamamoto H, Uchiyama A, Borges JB, Vidal Melo MF, Tucci MR, Amato MBP, Kavanagh BP, Costa ELV, Fujino Y.
Am J Respir Crit Care Med. 2018 May 15;197(10):1285-1296. doi: 10.1164/rccm.201706-1244OC.
High-level positive end expiratory pressure management in the surgical patient with acute respiratory distress syndrome.
Safcsak K, Nelson LD.
AACN Clin Issues. 1996 Nov;7(4):482-94; quiz 642-4. doi: 10.1097/00044067-199611000-00003.
Setting positive end-expiratory pressure: role in diaphragm-protective ventilation.
Wennen M, Claassen W, Heunks L.
Curr Opin Crit Care. 2024 Feb 1;30(1):61-68. doi: 10.1097/MCC.0000000000001126. Epub 2023 Dec 6.
