The Pathology of Asthma: What Is Obstructing Our View?
Aegerter H, Lambrecht BN.
Annu Rev Pathol. 2023 Jan 24;18:387-409. doi: 10.1146/annurev-pathol-042220-015902. Epub 2022 Oct 21.
Mucus Hypersecretion in Chronic Obstructive Pulmonary Disease and Its Treatment.
Shah BK, Singh B, Wang Y, Xie S, Wang C.
Mediators Inflamm. 2023 Jul 6;2023:8840594. doi: 10.1155/2023/8840594. eCollection 2023.
Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes.
Van Buren E, Radicioni G, Lester S, O'Neal WK, Dang H, Kasela S, Garudadri S, Curtis JL, Han MK, Krishnan JA, Wan ES, Silverman EK, Hastie A, Ortega VE, Lappalainen T, Nawijn MC, Berge MVD, Christenson SA, Li Y, Cho MH, Kesimer M, Kelada SNP.
PLoS Genet. 2023 Jun 23;19(6):e1010445. doi: 10.1371/journal.pgen.1010445. eCollection 2023 Jun.
Eosinophil-mucus interplay in severe asthma: Implications for treatment with biologicals.
Venegas Garrido C, Mukherjee M, Svenningsen S, Nair P.
Allergol Int. 2024 Jul;73(3):351-361. doi: 10.1016/j.alit.2024.03.001. Epub 2024 Mar 13.
Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection.
Packer RJ, Shrine N, Hall R, Melbourne CA, Thompson R, Williams AT, Paynton ML, Guyatt AL, Allen RJ, Lee PH, John C, Campbell A, Hayward C, de Vries M, Vonk JM, Davitte J, Hessel E, Michalovich D, Betts JC, Sayers I, Yeo A, Hall IP, Tobin MD, Wain LV.
Eur Respir J. 2023 Jun 15;61(6):2201667. doi: 10.1183/13993003.01667-2022. Print 2023 Jun.
Sputum short-chain fatty acids, microbiome, inflammation, and mucus plugging in obstructive airway disease.
Tanabe N, Matsumoto H, Morimoto C, Hirai T.
J Allergy Clin Immunol. 2025 May;155(5):1675-1680. doi: 10.1016/j.jaci.2025.01.031. Epub 2025 Feb 4.
Accelerated Lung Function Decline and Mucus-Microbe Evolution in Chronic Obstructive Pulmonary Disease.
Meldrum OW, Donaldson GC, Narayana JK, Ivan FX, Jaggi TK, Mac Aogáin M, Finney LJ, Allinson JP, Wedzicha JA, Chotirmall SH.
Am J Respir Crit Care Med. 2024 Aug 1;210(3):298-310. doi: 10.1164/rccm.202306-1060OC.
Mucus plugging on computed tomography and the sputum microbiome in patients with asthma, chronic obstructive pulmonary disease, and asthma-COPD overlap.
Tanabe N, Matsumoto H, Morimoto C, Hayashi Y, Sakamoto R, Oguma T, Nagasaki T, Sunadome H, Sato A, Sato S, Ohashi K, Tsukahara T, Hirai T.
Allergol Int. 2024 Oct;73(4):515-523. doi: 10.1016/j.alit.2024.05.004. Epub 2024 Jul 16.
Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis.
Ramsey KA, Chen ACH, Radicioni G, Lourie R, Martin M, Broomfield A, Sheng YH, Hasnain SZ, Radford-Smith G, Simms LA, Burr L, Thornton DJ, Bowler SD, Livengood S, Ceppe A, Knowles MR, Noone PG Sr, Donaldson SH, Hill DB, Ehre C, Button B, Alexis NE, Kesimer M, Boucher RC, McGuckin MA.
Am J Respir Crit Care Med. 2020 Mar 15;201(6):661-670. doi: 10.1164/rccm.201906-1219OC.
Airway IL-1β is related to disease severity and mucociliary function in bronchiectasis.
Perea L, Bottier M, Cant E, Richardson H, Dicker AJ, Shuttleworth M, Giam YH, Abo-Leyah H, Finch S, Huang JT, Shteinberg M, Goeminne PC, Polverino E, Altenburg J, Blasi F, Welte T, Aliberti S, Sibila O, Chalmers JD, Shoemark A.
Eur Respir J. 2024 Aug 15;64(2):2301966. doi: 10.1183/13993003.01966-2023. Print 2024 Aug.
