Identification of a missense variant in the WFS1 gene that causes a mild form of Wolfram syndrome and is associated with risk for type 2 diabetes in Ashkenazi Jewish individuals.
EP2 and EP3 receptors as therapeutic targets for underactive bladder/detrusor underactivity due to diabetic cystopathy in a type 1 diabetic rat model.
Sekido N, Otsuki T, Kida J, Mashimo H, Wakamatsu D, Okada H, Matsuya H.
Low Urin Tract Symptoms. 2020 Sep;12(3):285-291. doi: 10.1111/luts.12317. Epub 2020 May 14.
PMID:32410343
An adolescent male with persistent urinary symptoms.
Saha S, Sinha R.
Pediatr Nephrol. 2024 Nov;39(11):3209-3211. doi: 10.1007/s00467-024-06424-3. Epub 2024 Jun 6.
PMID:38842721
Juvenile diabetes mellitus, optic atrophy, hearing loss, diabetes insipidus, atonia of the urinary tract and bladder, and other abnormalities (Wolfram syndrome). A review of 88 cases from the literature with personal observations on 3 new patients.