Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
Shi Q, Chowdhury S, Ma R, Le KX, Hong S, Caldarone BJ, Stevens B, Lemere CA.
Sci Transl Med. 2017 May 31;9(392):eaaf6295. doi: 10.1126/scitranslmed.aaf6295.
Complement C3 deficiency: human, animal, and experimental models.
Singer L, Colten HR, Wetsel RA.
Pathobiology. 1994;62(1):14-28. doi: 10.1159/000163873.
C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue.
Götz P, Braumandl A, Kübler M, Kumaraswami K, Ishikawa-Ankerhold H, Lasch M, Deindl E.
Int J Mol Sci. 2021 May 28;22(11):5800. doi: 10.3390/ijms22115800.
Case Report: C3 deficiency in two siblings.
Bernacchia A, Ginaca A, Rotondo S, Tejada MP, Di Giovanni D.
Front Pediatr. 2024 Jul 24;12:1424380. doi: 10.3389/fped.2024.1424380. eCollection 2024.
C3 deficiency promotes pulmonary inflammation in AT1R-induced mouse model for systemic sclerosis.
Yin J, Verschoor A, Yue X, Goldmann T, Heidecke H, Riemekasten G, Petersen F, Yu X.
Front Immunol. 2024 Dec 16;15:1491324. doi: 10.3389/fimmu.2024.1491324. eCollection 2024.
Clinical and Genetic Spectrum of a Large Cohort With Total and Sub-total Complement Deficiencies.
El Sissy C, Rosain J, Vieira-Martins P, Bordereau P, Gruber A, Devriese M, de Pontual L, Taha MK, Fieschi C, Picard C, Frémeaux-Bacchi V.
Front Immunol. 2019 Aug 8;10:1936. doi: 10.3389/fimmu.2019.01936. eCollection 2019.
Homozygous human C3 deficiency. The role of C3 in antibody production, C-1s-induced vasopermeability, and cobra venom-induced passive hemolysis.
Alper CA, Colten HR, Gear JS, Rabson AR, Rosen FS.
J Clin Invest. 1976 Jan;57(1):222-9. doi: 10.1172/JCI108263.
Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.
Vernon KA, Ruseva MM, Cook HT, Botto M, Malik TH, Pickering MC.
J Am Soc Nephrol. 2016 May;27(5):1334-42. doi: 10.1681/ASN.2015030295. Epub 2015 Sep 15.
Complement C3 and C5 deficiency affects fracture healing.
Ehrnthaller C, Huber-Lang M, Nilsson P, Bindl R, Redeker S, Recknagel S, Rapp A, Mollnes T, Amling M, Gebhard F, Ignatius A.
PLoS One. 2013 Nov 18;8(11):e81341. doi: 10.1371/journal.pone.0081341. eCollection 2013.
The Different Responsiveness of C3- and C5-deficient Murine BM Cells to Oxidative Stress Explains Why C3 Deficiency, in Contrast to C5 Deficiency, Correlates with Better Pharmacological Mobilization and Engraftment of Hematopoietic Cells.
Konopko A, Łukomska A, Kucia M, Ratajczak MZ.
Stem Cell Rev Rep. 2025 Jan;21(1):59-67. doi: 10.1007/s12015-024-10792-6. Epub 2024 Sep 28.
