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NADH-CoQ reductase deficiency相关文献:
Disruption of mitochondrial complex I induces progressive parkinsonism.
González-Rodríguez P, Zampese E, Stout KA, Guzman JN, Ilijic E, Yang B, Tkatch T, Stavarache MA, Wokosin DL, Gao L, Kaplitt MG, López-Barneo J, Schumacker PT, Surmeier DJ.
Nature. 2021 Nov;599(7886):650-656. doi: 10.1038/s41586-021-04059-0. Epub 2021 Nov 3.
PMID:34732887
S100A8/A9(hi) neutrophils induce mitochondrial dysfunction and PANoptosis in endothelial cells via mitochondrial complex I deficiency during sepsis.
Wang Y, Shi Y, Shao Y, Lu X, Zhang H, Miao C.
Cell Death Dis. 2024 Jun 28;15(6):462. doi: 10.1038/s41419-024-06849-6.
PMID:38942784
Mitochondrial disease associated with complex I (NADH-CoQ oxidoreductase) deficiency.
Scheffler IE.
J Inherit Metab Dis. 2015 May;38(3):405-15. doi: 10.1007/s10545-014-9768-6. Epub 2014 Sep 16.
PMID:25224827
Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Martínez-Reyes I, Cardona LR, Kong H, Vasan K, McElroy GS, Werner M, Kihshen H, Reczek CR, Weinberg SE, Gao P, Steinert EM, Piseaux R, Budinger GRS, Chandel NS.
Nature. 2020 Sep;585(7824):288-292. doi: 10.1038/s41586-020-2475-6. Epub 2020 Jul 8.
PMID:32641834
AGK regulates the progression to NASH by affecting mitochondria complex I function.
Ding N, Wang K, Jiang H, Yang M, Zhang L, Fan X, Zou Q, Yu J, Dong H, Cheng S, Xu Y, Liu J.
Theranostics. 2022 Apr 4;12(7):3237-3250. doi: 10.7150/thno.69826. eCollection 2022.
PMID:35547757
Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver.
Yu M, Alimujiang M, Hu L, Liu F, Bao Y, Yin J.
Int J Biol Sci. 2021 Apr 12;17(7):1693-1707. doi: 10.7150/ijbs.54604. eCollection 2021.
PMID:33994854
CoQ imbalance drives reverse electron transport to disrupt liver metabolism.
Goncalves RLS, Wang ZB, Riveros JK, Parlakgül G, Inouye KE, Lee GY, Fu X, Saksi J, Rosique C, Hui ST, Coll M, Arruda AP, Burgess SC, Graupera I, Hotamışlıgil GS.
Nature. 2025 Jul;643(8073):1057-1065. doi: 10.1038/s41586-025-09072-1. Epub 2025 May 28.
PMID:40437093
Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT.
Nature. 2016 Oct 6;538(7623):123-126. doi: 10.1038/nature19754. Epub 2016 Sep 14.
PMID:27626371
Compensatory activity of the PC-ME1 metabolic axis underlies differential sensitivity to mitochondrial complex I inhibition.
Del Prado L, Jaraíz-Rodríguez M, Agro M, Zamora-Dorta M, Azpiazu N, Calleja M, Lopez-Manzaneda M, de Juan-Sanz J, Fernández-Rodrigo A, Esteban JA, Girona M, Quintana A, Balsa E.
Nat Commun. 2024 Oct 7;15(1):8682. doi: 10.1038/s41467-024-52968-1.
PMID:39375345
Selective deficiency of mitochondrial respiratory complex I subunits Ndufs4/6 causes tumor immunogenicity.
Liang J, Vitale T, Zhang X, Jackson TD, Yu D, Jedrychowski M, Gygi SP, Widlund HR, Wucherpfennig KW, Puigserver P.
Nat Cancer. 2025 Feb;6(2):323-337. doi: 10.1038/s43018-024-00895-x. Epub 2025 Jan 17.
PMID:39824999
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